Can C. diff come back?


Have you ever heard of C. diff or Clostridium difficile? 

It’s a type of bacterial infection that affects the digestive tract and can have serious health implications. C. diff can cause a range of symptoms, including diarrhea and inflammation of the colon. 

These infections often occur in people who have recently taken antibiotics, which can affect the balance of bacteria in the gut and allow C. diff to grow. C. diff infections are most common among people who are hospitalized or living in long-term healthcare facilities. 

However, it can also occur to people living in a normal community.

The length of time it takes for a C. diff test to come back (also known as the turnaround time) can vary depending on the type of test being used and the laboratory that is performing the test. Some C. diff tests can provide results within a few hours, while others may take several days to give a result.

If you or someone you know has a C. diff infection, treatment typically involves antibiotics. It’s also important to take steps to prevent the spread of the bacteria to others.

There are chances of reinfections if C. diff is not treated well. 

Can C. diff come back? 

Yes, it is possible for C. diff infections to recur. According to the Centers for Disease Control and Prevention (CDC), about 20% of people who have had a C. diff infection will have another infection within a few months of their first infection. 

The risk of recurrent infection is highest among people who are 65 years or older, have weakened immune systems, or have underlying medical conditions such as inflammatory bowel disease (IBD).

why does C. diff come back?

There are several factors that may increase the risk of recurrent C. diff infection, including the use of certain medications (such as proton pump inhibitors), inadequate treatment of the initial infection, and the presence of other types of bacteria in the gut that can interfere with the normal balance of the microbiome (the collection of bacteria and other microorganisms that live in the human body).


C. diff infections may recur a week or two after successful treatment, but it is also possible for recurrences to occur two months or more after the treatment is completed.

Also, there are some cases of re-infection of C. diff where other factors such as stress and alcohol have triggered them. There is some evidence that suggests that stress and alcohol consumption may increase the risk of recurrent infection. 

They can suppress the immune system and disrupt the normal balance of bacteria in the gut, thus leading to the development and recurrence of C. diff infections. This means that even after successful treatment, it is critical to be aware of the risk of recurrent infection.

Some of the symptoms of C. diff infection may include watery diarrhea, abdominal pain, fever, back pain and loss of appetite. In severe cases, the infection can cause a hole (perforation) in the colon, which can be life-threatening.

C. diff can be detected through various methods of tests like stool tests, tissue samples, and blood tests. The most common test used for detecting C. diff infection is a stool test, which involves collecting a sample of the person’s stool and sending it to a laboratory for analysis. 

Stool tests for C. diff can be performed using a variety of techniques, including enzyme immunoassay (EIA), polymerase chain reaction (PCR), and culture.


To reduce the risk of recurrent C. diff infection, it is important to follow the recommended treatment plan and take steps to prevent the spread of the bacteria to others. 

This may include proper hand hygiene, cleaning and disinfecting surfaces, taking antibiotics as directed to complete the entire course of treatment, and avoiding sharing personal items such as towels and washcloths.